5EHI

DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND MOLECULE BF287

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, C)	NS5 methyltransferase dengue virus	polymer	276	31206.8	2	UniProt (P27915)	Dengue virus type 3 (strain Philippines/H87/1956) (DENV-3)
2	C, E (A, C)	S-ADENOSYLMETHIONINE	non-polymer		398.4	2	Chemie (SAM)
3	D (A)	4-[[3-[(2-azanyl-4-chloranyl-phenyl)carbamoylamino]phenyl]sulfonylamino]benzoic acid	non-polymer		460.9	1	Chemie (5O3)
4	F, G (A, C)	water	water		18.0	872	Chemie (HOH)

Sequence modifications

A, C: 1 - 256 (UniProt: P27915)

PDB	External Database	Details
Thr 50	Ile 2540	conflict
Leu 257	-	expression tag
Gly 258	-	expression tag
Ala 259	-	expression tag
Gly 260	-	expression tag
Thr 261	-	expression tag
Arg 262	-	expression tag
His 263	-	expression tag
Val 264	-	expression tag
Asn 265	-	expression tag
Ala 266	-	expression tag
Glu 267	-	expression tag
Pro 268	-	expression tag
Glu 269	-	expression tag
Thr 270	-	expression tag
Pro 271	-	expression tag
Asn 272	-	expression tag
Met 273	-	expression tag
Asp 274	-	expression tag
Val 275	-	expression tag
Ile 276	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	62413.6
Non-Polymers*	Number of molecules	3
	Total formula weight	1257.8
All*	Total formula weight	63671.4

*Water molecules are not included.