5EEL
Grb7 SH2 with bicyclic peptide inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Growth factor receptor-bound protein 7 | polymer | 120 | 13690.7 | 6 | UniProt (Q14451) Pfam (PF00017) In PDB | Homo sapiens (Human) | B47,Epidermal growth factor receptor GRB-7,GRB7 adapter protein |
2 | L, M, N, P, Q... | Bicyclic Peptide Inhibitor | polymer | 9 | 1134.2 | 6 | synthetic construct | ||
3 | F, A, C, D, E | MALONIC ACID | non-polymer | 104.1 | 5 | Chemie (MLA) | |||
4 | F, A, B, C, D... | FORMIC ACID | non-polymer | 46.0 | 6 | Chemie (FMT) | |||
5 | F, A, B, C, D... | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
6 | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 415 - 532 (UniProt: Q14451)
PDB | External Database | Details |
---|---|---|
Gly 413 | - | expression tag |
Ser 414 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 88949.3 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 934.4 | |
All* | Total formula weight | 89883.7 |