5EEL
Grb7 SH2 with bicyclic peptide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Growth factor receptor-bound protein 7 | polymer | 120 | 13690.7 | 6 | UniProt (Q14451) Pfam (PF00017) | Homo sapiens (Human) | B47,Epidermal growth factor receptor GRB-7,GRB7 adapter protein |
| 2 | G, H, I, J, K... (L, M, N, P, Q...) | Bicyclic Peptide Inhibitor | polymer | 9 | 1134.2 | 6 | synthetic construct | ||
| 3 | AA, M, R, U, X (F, A, C, D, E) | MALONIC ACID | non-polymer | 104.1 | 5 | Chemie (MLA) | |||
| 4 | BA, N, P, S, V... (F, A, B, C, D...) | FORMIC ACID | non-polymer | 46.0 | 6 | Chemie (FMT) | |||
| 5 | CA, O, Q, T, W... (F, A, B, C, D...) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 6 | DA, EA, FA, GA, HA... (A, B, C, D, E...) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 415 - 532 (UniProt: Q14451)
| PDB | External Database | Details |
|---|---|---|
| Gly 413 | - | expression tag |
| Ser 414 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 88949.3 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 934.4 | |
| All* | Total formula weight | 89883.7 |
