5ED6
crystal structure of human Hint1 H114A mutant complexing with ATP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Histidine triad nucleotide-binding protein 1 | polymer | 128 | 13957.1 | 2 | UniProt (P49773) Pfam (PF01230) In PDB | Homo sapiens (Human) | Adenosine 5'-monophosphoramidase,Protein kinase C inhibitor 1,Protein kinase C-interacting protein 1,PKCI-1 |
2 | B | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
3 | B | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
4 | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 126 (UniProt: P49773)
PDB | External Database | Details |
---|---|---|
Ser -1 | - | expression tag |
Leu 0 | - | expression tag |
Ala 114 | His 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27914.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 585.5 | |
All* | Total formula weight | 28499.7 |