5ECX
Klebsiella pneumoniae DfrA1 complexed with NADPH and 6-ethyl-5-(3-(6-(pyridin-4-yl)benzo[d][1,3]dioxol-4-yl)but-1-yn-1-yl)pyrimidine-2,4-diamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Dehydrofolate reductase type I | polymer | 157 | 17592.0 | 2 | UniProt (A4GRC7) Pfam (PF00186) In PDB | Klebsiella pneumoniae | DfrA1,Dihydrofolate reductase |
| 2 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | A, B | 6-ethyl-5-[(3~{S})-3-(6-pyridin-4-yl-1,3-benzodioxol-4-yl)but-1-ynyl]pyrimidine-2,4-diamine | non-polymer | 387.4 | 2 | Chemie (5N1) | |||
| 4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | B | GLYOXYLIC ACID | non-polymer | 74.0 | 1 | Chemie (GLV) | |||
| 6 | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35184.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2427.8 | |
| All* | Total formula weight | 37611.8 |
