5ECE
Tankyrase 1 with Phthalazinone 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tankyrase-1 | polymer | 213 | 24305.6 | 4 | UniProt (O95271) Pfam (PF00644) | Homo sapiens (Human) | TANK1,ADP-ribosyltransferase diphtheria toxin-like 5,ARTD5,Poly [ADP-ribose] polymerase 5A,TNKS-1,TRF1-interacting ankyrin-related ADP-ribose polymerase,Tankyrase I |
| 2 | E, H, I, M, P... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 3 | F, J, N (A, B, C) | 2-[4-[3-[(4-oxidanylidene-3~{H}-phthalazin-1-yl)methyl]phenyl]carbonylpiperazin-1-yl]pyridine-3-carbonitrile | non-polymer | 450.5 | 3 | Chemie (5N2) | |||
| 4 | G, K, O, S (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | L (C) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | T, U, V, W (A, B, C, D) | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1105 - 1316 (UniProt: O95271)
| PDB | External Database | Details |
|---|---|---|
| Ala 1104 | - | expression tag |
| Ile 1266 | Met 1266 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 97222.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2106.6 | |
| All* | Total formula weight | 99328.9 |
