5EC9
Retinoic acid receptor alpha in complex with chiral dihydrobenzofuran benzoic acid 9a and a fragment of the coactivator TIF2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Retinoic acid receptor RXR-alpha | polymer | 210 | 23664.6 | 1 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| 2 | B (B) | LYS-HIS-LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN-ASP | polymer | 11 | 1405.7 | 1 | UniProt (by SIFTS) (Q15596) | Homo sapiens | |
| 3 | C (A) | 4-[(11S,15R)-4,4,7,7-Tetramethyl-16-oxatetracyclo[8.6.0.03,8.011,15]hexadeca-1(10),2,8-trien-11-yl]benzoic acid | non-polymer | 390.5 | 1 | Chemie (5LO) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A: 229 - 456 (UniProt: P19793)
| PDB | External Database | Details |
|---|---|---|
| - | Lys 245 | deletion |
| - | Thr 246 | deletion |
| - | Glu 247 | deletion |
| - | Thr 248 | deletion |
| - | Tyr 249 | deletion |
| - | Val 250 | deletion |
| - | Glu 251 | deletion |
| - | Ala 252 | deletion |
| - | Asn 253 | deletion |
| - | Met 254 | deletion |
| - | Gly 255 | deletion |
| - | Leu 256 | deletion |
| - | Asn 257 | deletion |
| - | Pro 258 | deletion |
| - | Ser 259 | deletion |
| - | Ser 260 | deletion |
| - | Pro 261 | deletion |
| - | Asn 262 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25070.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 390.5 | |
| All* | Total formula weight | 25460.8 |
