5EAM
Crystal structure of human WDR5 in complex with compound 9o
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | WD repeat-containing protein 5 | polymer | 312 | 34289.9 | 2 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (Human) | BMP2-induced 3-kb gene protein |
| 2 | C, P (A, B) | ~{N}-[5-(1~{H}-indol-5-yl)-2-(4-methylpiperazin-1-yl)phenyl]-3-methyl-benzamide | non-polymer | 424.5 | 2 | Chemie (5MN) | |||
| 3 | D, S, T, U, V (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | AA, BA, CA, DA, E... (B, A) | UNKNOWN ATOM OR ION | non-polymer | 25 | Chemie (UNX) | ||||
| 5 | Q (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | R (B) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 7 | KA, LA (A, B) | water | water | 18.0 | 328 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 334 (UniProt: P61964)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68579.8 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 1464.7 | |
| All* | Total formula weight | 70044.5 |
