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5EAM

Crystal structure of human WDR5 in complex with compound 9o

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
WD repeat-containing protein 5polymer31234289.92UniProt (P61964)
Pfam (PF00400)
Homo sapiens (Human)BMP2-induced 3-kb gene protein
2C, P
(A, B)
~{N}-[5-(1~{H}-indol-5-yl)-2-(4-methylpiperazin-1-yl)phenyl]-3-methyl-benzamidenon-polymer424.52Chemie (5MN)
3D, S, T, U, V
(A, B)
1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
4AA, BA, CA, DA, E...
(B, A)
UNKNOWN ATOM OR IONnon-polymer25Chemie (UNX)
5Q
(B)
SULFATE IONnon-polymer96.11Chemie (SO4)
6R
(B)
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer209.21Chemie (BTB)
7KA, LA
(A, B)
waterwater18.0328Chemie (HOH)
Sequence modifications
A, B: 24 - 334 (UniProt: P61964)
PDBExternal DatabaseDetails
Gly 23-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight68579.8
Non-Polymers*Number of molecules34
Total formula weight1464.7
All*Total formula weight70044.5
*Water molecules are not included.

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PDB entries from 2024-10-30

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