5E88
Crystal structure of Human galectin-3 CRD in complex with thienyl-1,2,3-triazolyl thiodigalactoside inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Galectin-3 | polymer | 139 | 15758.1 | 1 | UniProt (P17931) Pfam (PF00337) In PDB | Homo sapiens (Human) | Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,Galactoside-binding protein,GALBP,IgE-binding protein,L-31,Laminin-binding protein,Lectin L-29,Mac-2 antigen |
2 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
3 | A | 3-deoxy-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-1-thio-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranoside | non-polymer | 624.7 | 1 | Chemie (5KT) | |||
4 | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 114 - 250 (UniProt: P17931)
PDB | External Database | Details |
---|---|---|
Gly 112 | - | expression tag |
Pro 113 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 15758.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 660.2 | |
All* | Total formula weight | 16418.3 |