5E6C
Glucocorticoid receptor DNA binding domain - CCL2 NF-kB response element complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glucocorticoid receptor | polymer | 114 | 12759.8 | 2 | UniProt (P04150) Pfam (PF00105) | Homo sapiens (Human) | GR,Nuclear receptor subfamily 3 group C member 1 |
| 2 | C (C) | DNA (5'-D(*AP*GP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*AP*CP*T)-3') | polymer | 16 | 4882.2 | 1 | Homo sapiens | ||
| 3 | D (D) | DNA (5'-D(*AP*GP*TP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*AP*CP*T)-3') | polymer | 16 | 4913.2 | 1 | Homo sapiens | ||
| 4 | E, F, G, H (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A, B: 417 - 506 (UniProt: P04150)
| PDB | External Database | Details |
|---|---|---|
| Met 393 | - | initiating methionine |
| His 394 | - | expression tag |
| His 395 | - | expression tag |
| His 396 | - | expression tag |
| His 397 | - | expression tag |
| His 398 | - | expression tag |
| His 399 | - | expression tag |
| Ser 400 | - | expression tag |
| Ser 401 | - | expression tag |
| Gly 402 | - | expression tag |
| Val 403 | - | expression tag |
| Asp 404 | - | expression tag |
| Leu 405 | - | expression tag |
| Gly 406 | - | expression tag |
| Thr 407 | - | expression tag |
| Glu 408 | - | expression tag |
| Asn 409 | - | expression tag |
| Leu 410 | - | expression tag |
| Tyr 411 | - | expression tag |
| Phe 412 | - | expression tag |
| Gln 413 | - | expression tag |
| Ser 414 | - | expression tag |
| Asn 415 | - | expression tag |
| Ala 416 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 35315.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 35576.6 |
