5E68

High resolution crystal structure of LuxS - Quorum sensor molecular complex from Salmonella typhi at 1.58 Angstroms

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	S-ribosylhomocysteine lyase	polymer	179	20438.3	2	UniProt (Q8Z4D7) Pfam (PF02664) In PDB	Salmonella typhi	AI-2 synthesis protein,Autoinducer-2 production protein LuxS
2	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	A	(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran	non-polymer		150.1	1	Chemie (PAV)
4	B	METHIONINE	non-polymer		149.2	1	Chemie (MET)
5		water	water		18.0	227	Chemie (HOH)

Sequence modifications

A, B: 1 - 171 (UniProt: Q8Z4D7)

PDB	External Database	Details
Thr 21	Gly 21	engineered mutation
Leu 172	-	expression tag
Glu 173	-	expression tag
His 174	-	expression tag
His 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40876.6
Non-Polymers*	Number of molecules	4
	Total formula weight	430.2
All*	Total formula weight	41306.8

*Water molecules are not included.