5E68
High resolution crystal structure of LuxS - Quorum sensor molecular complex from Salmonella typhi at 1.58 Angstroms
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | S-ribosylhomocysteine lyase | polymer | 179 | 20438.3 | 2 | UniProt (Q8Z4D7) Pfam (PF02664) | Salmonella typhi | AI-2 synthesis protein,Autoinducer-2 production protein LuxS |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran | non-polymer | 150.1 | 1 | Chemie (PAV) | |||
| 4 | F (B) | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 171 (UniProt: Q8Z4D7)
| PDB | External Database | Details |
|---|---|---|
| Thr 21 | Gly 21 | engineered mutation |
| Leu 172 | - | expression tag |
| Glu 173 | - | expression tag |
| His 174 | - | expression tag |
| His 175 | - | expression tag |
| His 176 | - | expression tag |
| His 177 | - | expression tag |
| His 178 | - | expression tag |
| His 179 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40876.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 430.2 | |
| All* | Total formula weight | 41306.8 |
