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5E5G

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with D-tryptophan bound in the tryptophan and phenylalanine binding sites

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
3-deoxy-D-arabinoheptulosonate-7-phosphate synthasepolymer46450828.42UniProt (A0A0E8NFD1)
Pfam (PF01474)
UniProt (by SIFTS) (O53512)
Mycobacterium tuberculosis
2C, G, H, I, J
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
3D, K
(A, B)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
4E, F, L, M
(A, B)
D-TRYPTOPHANnon-polymer204.24Chemie (DTR)
5N, O
(A, B)
waterwater18.0648Chemie (HOH)
Sequence modifications
A, B: 1 - 462 (UniProt: A0A0E8NFD1)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight101656.8
Non-Polymers*Number of molecules11
Total formula weight1407.1
All*Total formula weight103063.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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