5E2Z
Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1) with LSTa
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (C, A, E) | Hemagglutinin | polymer | 333 | 37701.6 | 3 | UniProt (G8IPF0) Pfam (PF00509) | Influenza A virus (A/duck/Egypt/10185SS/2010(H5N1)) | HEMAGGLUTININ HA1 CHAIN |
| 2 | B, D, F (D, B, F) | Hemagglutinin | polymer | 180 | 20822.0 | 3 | UniProt (G8IPF0) Pfam (PF00509) | Influenza A virus | HEMAGGLUTININ HA2 CHAIN |
| 3 | G, K (G, K) | beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G46874CY) | |||
| 4 | H, L (H, L) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | branched | 471.4 | 2 | In PDB GlyTouCan (G30207PZ) | |||
| 5 | I (I) | beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 716.7 | 1 | In PDB GlyTouCan (G62810GW) | |||
| 6 | J (J) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 674.6 | 1 | In PDB GlyTouCan (G46776WR) | |||
| 7 | M, N, O (C, A, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 8 | P, Q, R, S, T... (C, D, A, B, E...) | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence modifications
C, A, E: 11 - 333 (UniProt: G8IPF0)
D, B, F: 2 - 175 (UniProt: G8IPF0)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Leu 226 | Gln 237 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Arg 176 | - | expression tag |
| Leu 177 | - | expression tag |
| Val 178 | - | expression tag |
| Pro 179 | - | expression tag |
| Arg 180 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 175570.9 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 3475.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 179709.7 |
