5E2M
Crystal structure of human carbonic anhydrase isozyme I with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Carbonic anhydrase 1 | polymer | 260 | 28835.1 | 2 | UniProt (P00915) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase I,Carbonic anhydrase B,CAB,Carbonic anhydrase I,CA-I |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide | non-polymer | 444.5 | 2 | Chemie (V14) | |||
| 4 | E (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | H, I (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 535 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 260 (UniProt: P00915)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57670.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1291.1 | |
| All* | Total formula weight | 58961.3 |
