5E22
The second PDZ domain of Ligand of Numb protein X 2 in the presence of an electric field of ~1 MV/cm along the crystallographic x axis, with eightfold extrapolation of structure factor differences.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | Ligand of Numb protein X 2 | polymer | 95 | 10310.7 | 2 | UniProt (Q8N448) Pfam (PF00595) In PDB | Homo sapiens (Human) | Numb-binding protein 2,PDZ domain-containing RING finger protein 1 |
| 2 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
B, A: 336 - 424 (UniProt: Q8N448)
| PDB | External Database | Details |
|---|---|---|
| Ser 334 | - | expression tag |
| Met 335 | - | expression tag |
| Leu 338 | Phe 338 | engineered mutation |
| Glu 425 | - | See REMARK 999 |
| Ile 426 | - | See REMARK 999 |
| Glu 427 | - | See REMARK 999 |
| Leu 428 | - | See REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20621.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 20713.6 |
