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5E22

The second PDZ domain of Ligand of Numb protein X 2 in the presence of an electric field of ~1 MV/cm along the crystallographic x axis, with eightfold extrapolation of structure factor differences.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, A)
Ligand of Numb protein X 2polymer9510310.72UniProt (Q8N448)
Pfam (PF00595)
Homo sapiens (Human)Numb-binding protein 2,PDZ domain-containing RING finger protein 1
2C
(B)
GLYCEROLnon-polymer92.11Chemie (GOL)
3D, E
(B, A)
waterwater18.0165Chemie (HOH)
Sequence modifications
B, A: 336 - 424 (UniProt: Q8N448)
PDBExternal DatabaseDetails
Ser 334-expression tag
Met 335-expression tag
Leu 338Phe 338engineered mutation
Glu 425-See REMARK 999
Ile 426-See REMARK 999
Glu 427-See REMARK 999
Leu 428-See REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight20621.5
Non-Polymers*Number of molecules1
Total formula weight92.1
All*Total formula weight20713.6
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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