5E1I
Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 2 with carbapenem drug T210
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | L,D-transpeptidase 2 | polymer | 370 | 39532.0 | 2 | UniProt (I6Y9J2) Pfam (PF17964) Pfam (PF03734) In PDB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | LDT 2,Ldt(Mt2) |
| 2 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 3 | A | (2S,3R,4R)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-(methylsulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid | non-polymer | 259.3 | 1 | Chemie (6B8) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A, B: 42 - 408 (UniProt: I6Y9J2)
| PDB | External Database | Details |
|---|---|---|
| Gly 39 | - | expression tag |
| His 40 | - | expression tag |
| Met 41 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79064.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 374.4 | |
| All* | Total formula weight | 79438.4 |
