5E1E
Human JAK1 kinase in complex with compound 30 at 2.30 Angstroms resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tyrosine-protein kinase JAK1 | polymer | 290 | 33489.2 | 2 | UniProt (P23458) Pfam (PF07714) In PDB | Homo sapiens (Human) | Janus kinase 1,JAK-1 |
| 2 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 3 | A, B | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-N-(piperidin-4-ylmethyl)-3H-imidazo[4,5-b]pyridin-7-amine | non-polymer | 419.9 | 2 | Chemie (5JG) | |||
| 4 | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66978.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 945.9 | |
| All* | Total formula weight | 67924.3 |
