5DZJ
Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 2 with carbapenem drug T206 in conformation A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | L,D-transpeptidase 2 | polymer | 370 | 39532.0 | 2 | UniProt (I6Y9J2) Pfam (PF17964) Pfam (PF03734) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | LDT 2,Ldt(Mt2) |
| 2 | C, D (A, B) | (2~{R},3~{R},4~{R})-4-methyl-3-(2-oxidanylidene-2-propoxy-ethyl)sulfanyl-5-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-2-carboxylic acid | non-polymer | 345.4 | 2 | Chemie (6B7) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 635 | Chemie (HOH) |
Sequence modifications
A, B: 42 - 408 (UniProt: I6Y9J2)
| PDB | External Database | Details |
|---|---|---|
| Gly 39 | - | expression tag |
| His 40 | - | expression tag |
| Met 41 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79064.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 690.8 | |
| All* | Total formula weight | 79754.8 |
