5DYJ
Mysosin heavy chain kinase A catalytic domain mutant - D663A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Myosin heavy chain kinase A | polymer | 307 | 34518.4 | 2 | UniProt (P42527) Pfam (PF02816) | Dictyostelium discoideum (Slime mold) | MHCK-A |
| 2 | C, G (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) PubChem (1061) | |||
| 3 | D, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, I (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 5 | F, J (A, B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
A, B: 552 - 841 (UniProt: P42527)
| PDB | External Database | Details |
|---|---|---|
| Met 535 | - | initiating methionine |
| Gly 536 | - | expression tag |
| Gly 537 | - | expression tag |
| His 538 | - | expression tag |
| His 539 | - | expression tag |
| His 540 | - | expression tag |
| His 541 | - | expression tag |
| His 542 | - | expression tag |
| His 543 | - | expression tag |
| Gly 544 | - | expression tag |
| Glu 545 | - | expression tag |
| Asn 546 | - | expression tag |
| Leu 547 | - | expression tag |
| Tyr 548 | - | expression tag |
| Phe 549 | - | expression tag |
| Gln 550 | - | expression tag |
| Gly 551 | - | expression tag |
| Ala 663 | Asp 663 | engineered mutation |
| Asn 818 | Lys 818 | conflict |
| Gln 819 | Lys 819 | conflict |
| Lys 828 | Met 828 | conflict |
| Ala 829 | Pro 829 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69036.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1199.4 | |
| All* | Total formula weight | 70236.1 |
