5DXU
p110delta/p85alpha with GDC-0326
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | polymer | 1043 | 119501.8 | 1 | UniProt (O00329) Pfam (PF02192) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB | Homo sapiens (Human) | PtdIns-3-kinase subunit delta,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,p110delta |
| 2 | B | Phosphatidylinositol 3-kinase regulatory subunit alpha | polymer | 169 | 20879.6 | 1 | UniProt (P23727) Pfam (PF16454) In PDB | Bos taurus (Bovine) | PtdIns-3-kinase regulatory subunit alpha,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,PtdIns-3-kinase regulatory subunit p85-alpha |
| 3 | A | (2S)-2-({2-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}oxy)propanamide | non-polymer | 382.4 | 1 | Chemie (5H5) | |||
| 4 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 140381.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 382.4 | |
| All* | Total formula weight | 140763.8 |
