5DXH

p110alpha/p85alpha with compound 5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, D)	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	polymer	1067	124313.8	2	UniProt (P42336) Pfam (PF02192) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454)	Homo sapiens (Human)	PtdIns-3-kinase subunit alpha,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha,p110alpha,Phosphoinositide-3-kinase catalytic alpha polypeptide,Serine/threonine protein kinase PIK3CA
2	B, D (B, E)	Phosphatidylinositol 3-kinase regulatory subunit alpha	polymer	169	20879.6	2	UniProt (P23727) Pfam (PF16454)	Bos taurus (Bovine)	PtdIns-3-kinase regulatory subunit alpha,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,PtdIns-3-kinase regulatory subunit p85-alpha
3	E, F (A, D)	methyl {2-[4-(2-chlorophenyl)-4H-1,2,4-triazol-3-yl]-4,5-dihydrothieno[3,2-d][1]benzoxepin-8-yl}carbamate	non-polymer		452.9	2	Chemie (5H2)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	290386.7
Non-Polymers*	Number of molecules	2
	Total formula weight	905.8
All*	Total formula weight	291292.5

*Water molecules are not included.