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5DWS

Crystal Structure of ITCH WW3 domain in complex with TXNIP peptide

Replaces:  4RRE
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, C, E, G)
E3 ubiquitin-protein ligase Itchy homologpolymer475412.04UniProt (Q96J02)
Pfam (PF00397)
Homo sapiens (Human)Itch,Atrophin-1-interacting protein 4,AIP4,NFE2-associated polypeptide 1,NAPP1
2B, D, F, H
(B, D, F, H)
txnippolymer141359.64UniProt (by SIFTS) (Q9H3M7)Homo sapiens
3AA, BA, CA, DA, EA...
(G, H, A, C, E...)
UNKNOWN ATOM OR IONnon-polymer26Chemie (UNX)
4IA, JA, KA, LA, MA...
(A, B, C, D, E...)
waterwater18.073Chemie (HOH)
Sequence modifications
A, C, E, G: 436 - 474 (UniProt: Q96J02)
PDBExternal DatabaseDetails
Gly 428-expression tag
Arg 429-expression tag
Arg 430-expression tag
Ala 431-expression tag
Ser 432-expression tag
Val 433-expression tag
Glu 434-expression tag
Leu 435-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight27086.2
Non-Polymers*Number of molecules26
Total formula weight0.0
All*Total formula weight27086.2
*Water molecules are not included.

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PDB entries from 2024-10-30

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