5DVO

Fc K392D/K409D homodimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ig gamma-1 chain C region	polymer	227	25584.8	2	UniProt (P01857) Pfam (PF07654)	Homo sapiens (Human)
2	C, D (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	E, F (A, B)	water	water		18.0	142	Chemie (HOH)

Sequence modifications

A, B: 221 - 447 (UniProt: P01857)

PDB	External Database	Details
Glu 356	Asp 239	variant
Met 358	Leu 241	variant
Asp 392	Lys 275	engineered mutation
Asp 409	Lys 292	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51169.7
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	51361.8

*Water molecules are not included.