5DU9
First condensation domain of the calcium-dependent antibiotic synthetase in complex with substrate analogue 2a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | CDA peptide synthetase I | polymer | 450 | 48508.5 | 2 | UniProt (Q9Z4X6) Pfam (PF00668) In PDB | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) | |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | A, B | (2S)-2-amino-N-butyl-propanamide | non-polymer | 144.2 | 2 | Chemie (UM2) | |||
| 5 | water | water | 18.0 | 1271 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 449 (UniProt: Q9Z4X6)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Cys 17 | Glu 17 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97017.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 455.4 | |
| All* | Total formula weight | 97472.4 |
