5DTO
Dengue virus full length NS5 complexed with viral Cap 0-RNA and SAH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NS5 | polymer | 892 | 102830.6 | 1 | UniProt (A1XTB9) Pfam (PF01728) Pfam (PF00972) Pfam (PF20483) UniProt (by SIFTS) (Q6YMS4) | Dengue virus 3 | |
| 2 | B (B) | RNA (5'-R(P*AP*GP*UP*U)-3') | polymer | 4 | 1241.8 | 1 | Dengue virus | ||
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 5 | F, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | G (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | H (B) | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE | non-polymer | 458.2 | 1 | Chemie (M7G) | |||
| 8 | J, K (A, B) | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence modifications
A: 6 - 895 (UniProt: A1XTB9)
| PDB | External Database | Details |
|---|---|---|
| Ser 4 | - | expression tag |
| Met 5 | - | expression tag |
| Ile 72 | Val 2562 | conflict |
| Leu 366 | Met 2856 | conflict |
| Val 480 | Ala 2970 | conflict |
| Ile 748 | Leu 3238 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 104072.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1081.1 | |
| All* | Total formula weight | 105153.5 |
