5DJR
Crystal structure of human FPPS in complex with biaryl compound 6
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | F | Farnesyl pyrophosphate synthase | polymer | 350 | 40183.9 | 1 | UniProt (P14324) Pfam (PF00348) In PDB | Homo sapiens (Human) | FPS,(2E,6E)-farnesyl diphosphate synthase,Dimethylallyltranstransferase,Farnesyl diphosphate synthase,Geranyltranstransferase |
2 | F | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
3 | F | 1H,1'H-4,4'-biindole-2-carboxylic acid | non-polymer | 276.3 | 1 | Chemie (5BK) | |||
4 | F | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
5 | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
F: 6 - 353 (UniProt: P14324)
PDB | External Database | Details |
---|---|---|
Gly 4 | - | expression tag |
Pro 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40183.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 555.4 | |
All* | Total formula weight | 40739.3 |