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5DJP

Crystal structure of human FPPS in complex with biaryl compound 5

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1FFarnesyl pyrophosphate synthasepolymer35040183.91UniProt (P14324)
Pfam (PF00348)
In PDB
Homo sapiens (Human)FPS,(2E,6E)-farnesyl diphosphate synthase,Dimethylallyltranstransferase,Farnesyl diphosphate synthase,Geranyltranstransferase
2F4-(naphthalen-1-yl)-1H-indole-2-carboxylic acidnon-polymer287.31Chemie (5BJ)
3FPHOSPHATE IONnon-polymer95.01Chemie (PO4)
4waterwater18.055Chemie (HOH)
Sequence modifications
F: 6 - 353 (UniProt: P14324)
PDBExternal DatabaseDetails
Gly 4-expression tag
Pro 5-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40183.9
Non-Polymers*Number of molecules2
Total formula weight382.3
All*Total formula weight40566.1
*Water molecules are not included.

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PDB entries from 2024-07-31

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