5DG0
Human APE1 phosphorothioate substrate complex with Mn2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA-(apurinic or apyrimidinic site) lyase | polymer | 276 | 31188.5 | 2 | UniProt (P27695) Pfam (PF03372) | Homo sapiens (Human) | APEX nuclease,APEN,Apurinic-apyrimidinic endonuclease 1,APE-1,REF-1,Redox factor-1 |
| 2 | C (P) | DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(OMC)P*(48Z)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3') | polymer | 21 | 6396.1 | 1 | synthetic construct | ||
| 3 | D (V) | DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3') | polymer | 21 | 6465.2 | 1 | synthetic construct | ||
| 4 | E, F, G, M, O... (A, B, P) | MANGANESE (II) ION | non-polymer | 54.9 | 7 | Chemie (MN) | |||
| 5 | H, I, J, K, N (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 6 | L (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | R, S, T, U (A, B, P, V) | water | water | 18.0 | 470 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 75238.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 730.4 | |
| All* | Total formula weight | 75968.7 |
