5DFV

CRYSTAL STRUCTURE OF HUMAN CD81 LARGE EXTRACELLULAR LOOP IN COMPLEX WITH MURINE FAB FRAGMENT K04

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	CD81 antigen	polymer	99	10947.1	2	UniProt (P60033) Pfam (PF00335)	Homo sapiens (Human)	26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1,Tetraspanin-28,Tspan-28
2	C, E (C, E)	FAB HEAVY CHAIN	polymer	222	23454.5	2		Mus musculus (HOUSE MOUSE)
3	D, F (D, F)	FAB LIGHT CHAIN	polymer	218	24187.8	2		Mus musculus (HOUSE MOUSE)
4	G, H, I (C, D, E)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A, B: 112 - 202 (UniProt: P60033)

PDB	External Database	Details
Gly 110	-	expression tag
Ser 111	-	expression tag
His 202	Leu 202	conflict
His 203	-	expression tag
His 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	117178.7
All*	Total formula weight	117178.7

*Water molecules are not included.