5DAB
Crystal structure of FTO-IN115
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-ketoglutarate-dependent dioxygenase FTO | polymer | 479 | 55090.2 | 1 | UniProt (Q9C0B1) Pfam (PF12933) Pfam (PF12934) | Homo sapiens (Human) | Fat mass and obesity-associated protein |
| 2 | B, C, D, E, F... (A) | CHLORIDE ION | non-polymer | 35.5 | 9 | Chemie (CL) | |||
| 3 | K (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 4 | L (A) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
| 5 | M (A) | N-(5-chloro-2,4-dihydroxyphenyl)-1-phenylcyclobutanecarboxamide | non-polymer | 317.8 | 1 | Chemie (58W) | |||
| 6 | N (A) | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
A: 32 - 505 (UniProt: Q9C0B1)
| PDB | External Database | Details |
|---|---|---|
| Leu 27 | - | expression tag |
| Glu 28 | - | expression tag |
| Ser 29 | - | expression tag |
| His 30 | - | expression tag |
| Met 31 | - | expression tag |
| Asp 188 | Gln 188 | conflict |
| Val 189 | Asp 189 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 55090.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 838.8 | |
| All* | Total formula weight | 55929.0 |
