5D9J
2009 H1N1 PA endonuclease mutant F105S in complex with L-742,001
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polymerase acidic protein | polymer | 187 | 21910.1 | 1 | UniProt (C3W5S0) | Influenza A virus | PA endonuclease |
| 2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D (A) | (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid | non-polymer | 413.9 | 1 | Chemie (0N8) | |||
| 4 | E (A) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A: 1 - 50 (UniProt: C3W5S0)
A: 54 - 177 (UniProt: C3W5S0)
A: 54 - 177 (UniProt: C3W5S0)
| PDB | External Database | Details |
|---|---|---|
| Gly 51 | - | linker |
| Gly 52 | - | linker |
| Ser 53 | - | linker |
| Ser 86 | Phe 105 | engineered mutation |
| Ala 178 | - | expression tag |
| Ala 179 | - | expression tag |
| Ala 180 | - | expression tag |
| Glu 181 | - | expression tag |
| Leu 182 | - | expression tag |
| Ala 183 | - | expression tag |
| Leu 184 | - | expression tag |
| Val 185 | - | expression tag |
| Pro 186 | - | expression tag |
| Arg 187 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21910.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 523.8 | |
| All* | Total formula weight | 22433.8 |
