5D8U
2009 H1N1 PA endonuclease mutant E119D in complex with L-742,001
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Polymerase acidic protein | polymer | 197 | 23134.3 | 1 | UniProt (C3W5S0) In PDB | Influenza A virus | PA endonuclease |
2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
3 | A | (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid | non-polymer | 413.9 | 1 | Chemie (0N8) | |||
4 | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
A: 1 - 50 (UniProt: C3W5S0)
A: 73 - 196 (UniProt: C3W5S0)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 51 | - | linker |
Gly 52 | - | linker |
Ser 53 | - | linker |
Asp 119 | Glu 119 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23134.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 523.8 | |
All* | Total formula weight | 23658.1 |