5D0H
Crystal Structure of triple mutant (KDA to EGY) of an adenylyl cyclase Ma1120 from Mycobacterium avium in complex with ATP and calcium ion
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cyclase | polymer | 177 | 19621.3 | 2 | UniProt (V7LAR8) | Mycobacterium avium subsp. avium 10-9275 | |
| 2 | C, E (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 3 | D, F (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence modifications
A, B: 106 - 275 (UniProt: V7LAR8)
| PDB | External Database | Details |
|---|---|---|
| Phe 99 | - | expression tag |
| Gln 100 | - | expression tag |
| Gly 101 | - | expression tag |
| Ala 102 | - | expression tag |
| Met 103 | - | expression tag |
| Gly 104 | - | expression tag |
| Ser 105 | - | expression tag |
| Glu 153 | Lys 153 | engineered mutation |
| Gly 209 | Asp 209 | engineered mutation |
| Tyr 219 | Ala 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39242.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1094.5 | |
| All* | Total formula weight | 40337.2 |
