5CVN

WDR48 (2-580):USP46~ubiquitin ternary complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	WD repeat-containing protein 48	polymer	598	67150.9	1	UniProt (Q8TAF3) Pfam (PF00400) Pfam (PF11816)	Homo sapiens (Human)	USP1-associated factor 1,WD repeat endosomal protein,p80
2	B (B)	Ubiquitin carboxyl-terminal hydrolase 46	polymer	358	41959.6	1	UniProt (P62068) Pfam (PF00443)	Homo sapiens (Human)	Deubiquitinating enzyme 46,Ubiquitin thioesterase 46,Ubiquitin-specific-processing protease 46
3	C (D)	Polyubiquitin-B	polymer	96	10748.2	1	UniProt (P0CG47) Pfam (PF00240)	Homo sapiens (Human)
4	D (B)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
5	E, F, G (A, B, D)	water	water		18.0	34	Chemie (HOH)

Sequence modifications

A: 2 - 580 (UniProt: Q8TAF3)

PDB	External Database	Details
Met -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
Gly -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag
Gly 581	-	expression tag
Asn 582	-	expression tag
Ser 583	-	expression tag

B: 25 - 366 (UniProt: P62068)

PDB	External Database	Details
Met 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
Gly 16	-	expression tag
Glu 17	-	expression tag
Asn 18	-	expression tag
Leu 19	-	expression tag
Tyr 20	-	expression tag
Phe 21	-	expression tag
Gln 22	-	expression tag
Gly 23	-	expression tag
Ser 24	-	expression tag

D: 1 - 76 (UniProt: P0CG47)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	119858.7
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	119924.1

*Water molecules are not included.