5CVG

Crystal Structure of CK2alpha with a novel closed conformation of the aD loop

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Casein kinase II subunit alpha	polymer	351	41380.7	1	UniProt (P68400) Pfam (PF00069)	Homo sapiens (Human)	CK II alpha
2	B, C, D, E (A)	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
3	F (A)	water	water		18.0	301	Chemie (HOH)

Sequence modifications

A: 2 - 329 (UniProt: P68400)

PDB	External Database	Details
Gly -21	-	expression tag
Ser -20	-	expression tag
Met -19	-	expression tag
Asp -18	-	expression tag
Ile -17	-	expression tag
Glu -16	-	expression tag
Phe -15	-	expression tag
Asp -14	-	expression tag
Asp -13	-	expression tag
Asp -12	-	expression tag
Ala -11	-	expression tag
Asp -10	-	expression tag
Asp -9	-	expression tag
Asp -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Gly 1	-	expression tag
Ser 21	Arg 21	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41380.7
Non-Polymers*	Number of molecules	4
	Total formula weight	236.2
All*	Total formula weight	41616.9

*Water molecules are not included.