5CVE

Crystal Structure of human NRMT1 in complex with dimethylated fly H2B peptide and SAH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	N-terminal Xaa-Pro-Lys N-methyltransferase 1	polymer	243	27589.4	2	UniProt (Q9BV86) Pfam (PF05891)	Homo sapiens (Human)	Alpha N-terminal protein methyltransferase 1A,Methyltransferase-like protein 11A,N-terminal RCC1 methyltransferase,X-Pro-Lys N-terminal protein methyltransferase 1A,NTM1A
2	C, D (D, E)	N-terminal peptide from Histone H2B	polymer	9	887.1	2	UniProt (P02283)	Drosophila melanogaster
3	E, F (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
4	G, H, I, J (A, B, D, E)	water	water		18.0	754	Chemie (HOH)

Sequence modifications

A, B: 1 - 223 (UniProt: Q9BV86)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	56952.9
Non-Polymers*	Number of molecules	2
	Total formula weight	768.8
All*	Total formula weight	57721.8

*Water molecules are not included.