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5CVD

Crystal structure of human NRMT1 in complex with alpha-N-dimethylated human CENP-A peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
N-terminal Xaa-Pro-Lys N-methyltransferase 1polymer24327589.42UniProt (Q9BV86)
Pfam (PF05891)
Homo sapiens (Human)Alpha N-terminal protein methyltransferase 1A,Methyltransferase-like protein 11A,N-terminal RCC1 methyltransferase,X-Pro-Lys N-terminal protein methyltransferase 1A,NTM1A
2C, D
(D, E)
N-teminal peptide from Histone H3-like centromeric protein Apolymer91142.42UniProt (P49450)Homo sapiens (Human)Centromere autoantigen A,Centromere protein A,CENP-A
3E, F
(A, B)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
4G, H, I, J
(A, B, D, E)
waterwater18.0727Chemie (HOH)
Sequence modifications
A, B: 1 - 223 (UniProt: Q9BV86)
PDBExternal DatabaseDetails
Met -19-expression tag
Gly -18-expression tag
Ser -17-expression tag
Ser -16-expression tag
His -15-expression tag
His -14-expression tag
His -13-expression tag
His -12-expression tag
His -11-expression tag
His -10-expression tag
Ser -9-expression tag
Ser -8-expression tag
Gly -7-expression tag
Leu -6-expression tag
Val -5-expression tag
Pro -4-expression tag
Arg -3-expression tag
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight57463.6
Non-Polymers*Number of molecules2
Total formula weight768.8
All*Total formula weight58232.4
*Water molecules are not included.

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PDB entries from 2024-10-30

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