5CVD
Crystal structure of human NRMT1 in complex with alpha-N-dimethylated human CENP-A peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | N-terminal Xaa-Pro-Lys N-methyltransferase 1 | polymer | 243 | 27589.4 | 2 | UniProt (Q9BV86) Pfam (PF05891) | Homo sapiens (Human) | Alpha N-terminal protein methyltransferase 1A,Methyltransferase-like protein 11A,N-terminal RCC1 methyltransferase,X-Pro-Lys N-terminal protein methyltransferase 1A,NTM1A |
2 | C, D (D, E) | N-teminal peptide from Histone H3-like centromeric protein A | polymer | 9 | 1142.4 | 2 | UniProt (P49450) | Homo sapiens (Human) | Centromere autoantigen A,Centromere protein A,CENP-A |
3 | E, F (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
4 | G, H, I, J (A, B, D, E) | water | water | 18.0 | 727 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 223 (UniProt: Q9BV86)
PDB | External Database | Details |
---|---|---|
Met -19 | - | expression tag |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 57463.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 768.8 | |
All* | Total formula weight | 58232.4 |