5CTI

Crystal structure of the type IX collagen NC2 hetero-trimerization domain with a guest fragment a2a1a1 of type I collagen (native form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Collagen alpha-1(I) chain,Collagen alpha-1(IX) chain	polymer	71	7021.0	1	UniProt (P02452) UniProt (P20849) In PDB	Homo sapiens (Human)	Alpha-1 type I collagen
2	B	Collagen alpha-2(I) chain,Collagen alpha-2(IX) chain	polymer	71	6895.7	1	UniProt (P08123) UniProt (Q14055) In PDB	Homo sapiens (Human)	Alpha-2 type I collagen
3	C	Collagen alpha-1(I) chain,Collagen alpha-3(IX) chain	polymer	72	6999.0	1	UniProt (P02452) UniProt (Q14050) Pfam (PF01391) In PDB	Homo sapiens (Human)	Alpha-1 type I collagen
4	B, C	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5		water	water		18.0	145	Chemie (HOH)

Sequence modifications

A: 15 - 26 (UniProt: P02452)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag
Gly 3	-	expression tag
Pro 4	-	expression tag
Pro 5	-	expression tag
Gly 6	-	expression tag
Pro 7	-	expression tag
Pro 8	-	expression tag
Gly 9	-	expression tag
Pro 10	-	expression tag
Pro 11	-	expression tag
Gly 12	-	expression tag
Pro 13	-	expression tag
Pro 14	-	expression tag
Gly 27	-	linker
Pro 28	-	linker
Pro 29	-	linker
Gly 30	-	linker
Pro 31	-	linker
Pro 32	-	linker
Gly 33	-	linker
Pro 34	-	linker
Pro 35	-	linker

A: 36 - 71 (UniProt: P20849)
B: 15 - 26 (UniProt: P08123)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag
Gly 3	-	expression tag
Pro 4	-	expression tag
Pro 5	-	expression tag
Gly 6	-	expression tag
Pro 7	-	expression tag
Pro 8	-	expression tag
Gly 9	-	expression tag
Pro 10	-	expression tag
Pro 11	-	expression tag
Gly 12	-	expression tag
Pro 13	-	expression tag
Pro 14	-	expression tag
Gly 27	-	linker
Pro 28	-	linker
Pro 29	-	linker
Gly 30	-	linker
Pro 31	-	linker
Pro 32	-	linker
Gly 33	-	linker
Pro 34	-	linker
Pro 35	-	linker

B: 36 - 71 (UniProt: Q14055)
C: 15 - 26 (UniProt: P02452)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag
Gly 3	-	expression tag
Pro 4	-	expression tag
Pro 5	-	expression tag
Gly 6	-	expression tag
Pro 7	-	expression tag
Pro 8	-	expression tag
Gly 9	-	expression tag
Pro 10	-	expression tag
Pro 11	-	expression tag
Gly 12	-	expression tag
Pro 13	-	expression tag
Pro 14	-	expression tag
Gly 27	-	linker
Pro 28	-	linker
Pro 29	-	linker
Gly 30	-	linker
Pro 31	-	linker
Pro 32	-	linker
Gly 33	-	linker
Pro 34	-	linker
Pro 35	-	linker

C: 36 - 72 (UniProt: Q14050)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	20915.7
Non-Polymers*	Number of molecules	3
	Total formula weight	276.3
All*	Total formula weight	21192.0

*Water molecules are not included.