5CP9
The structure of the NK1 fragment of HGF/SF complexed with MB605
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hepatocyte growth factor | polymer | 183 | 21172.3 | 2 | UniProt (P14210) Pfam (PF00024) Pfam (PF00051) | Homo sapiens (Human) | Hepatopoietin-A,Scatter factor,SF |
| 2 | C (B) | 3-(furan-2-yl)propanoic acid | non-polymer | 140.1 | 1 | Chemie (6O5) | |||
| 3 | D (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 234 | Chemie (HOH) |
Sequence modifications
A, B: 28 - 210 (UniProt: P14210)
| PDB | External Database | Details |
|---|---|---|
| Val 29 | Ala 29 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42344.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 202.2 | |
| All* | Total formula weight | 42546.8 |
