5COO
X-ray crystal structure of wild type HIV-1 protease in complex with GRL-085
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | HIV-1 protease | polymer | 99 | 10802.8 | 2 | UniProt (G0X8E3) Pfam (PF00077) UniProt (by SIFTS) (G0X8E8) In PDB | Human immunodeficiency virus 1 | |
| 2 | B | (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-1-(4-methoxyphenyl)-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}butan-2-yl]carbamate | non-polymer | 622.7 | 1 | Chemie (52Z) | |||
| 3 | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: G0X8E3)
| PDB | External Database | Details |
|---|---|---|
| Asn 25 | Asp 25 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21605.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 622.7 | |
| All* | Total formula weight | 22228.3 |
