5CNV
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to GDP and TTP at 3.20 Angstroms resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ribonucleoside-diphosphate reductase 1 subunit alpha | polymer | 761 | 85877.1 | 4 | UniProt (P00452) Pfam (PF03477) Pfam (PF00317) Pfam (PF02867) | Escherichia coli (strain K12) | Protein B1,Ribonucleoside-diphosphate reductase 1 R1 subunit,Ribonucleotide reductase 1 |
| 2 | E, F, G, H (E, F, G, H) | Ribonucleoside-diphosphate reductase 1 subunit beta | polymer | 375 | 43426.9 | 4 | UniProt (P69924) Pfam (PF00268) | Escherichia coli (strain K12) | Protein B2,Protein R2,Ribonucleotide reductase 1 |
| 3 | AA, I, O, U (D, A, B, C) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 4 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | BA, J, P, V (D, A, B, C) | 2'-DEOXYADENOSINE-5'-DIPHOSPHATE | non-polymer | 411.2 | 4 | Chemie (DAT) PubChem (620) PubChem (177678916) PubChem (188966) PubChem (53477733) PubChem (56988235) PubChem (92132338) PubChem (92436381) PubChem (92449117) PubChem (92449118) PubChem (92449116) PubChem (92449115) | |||
| 5 | CA, FA, K, N, Q... (D, A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) PubChem (888) | |||
| 6 | DA, EA, L, M, R... (D, A, B, C) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 8 | Chemie (TTP) | |||
| 7 | GA, HA, IA, JA (E, F, G, H) | MU-OXO-DIIRON | non-polymer | 127.7 | 4 | Chemie (FEO) | |||
| 8 | KA, LA, MA, NA, OA... (A, B, C, D, E...) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 517215.8 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 7980.2 | |
| All* | Total formula weight | 525195.9 |
