5CNS
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to CDP and dATP at 2.97 Angstroms resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ribonucleoside-diphosphate reductase 1 subunit alpha | polymer | 761 | 85877.1 | 4 | UniProt (P00452) Pfam (PF03477) Pfam (PF00317) Pfam (PF02867) | Escherichia coli (strain K12) | Protein B1,Ribonucleoside-diphosphate reductase 1 R1 subunit,Ribonucleotide reductase 1 |
| 2 | E, F, G, H (E, F, G, H) | Ribonucleoside-diphosphate reductase 1 subunit beta | polymer | 375 | 43426.9 | 4 | UniProt (P69924) Pfam (PF00268) | Escherichia coli (strain K12) | Protein B2,Protein R2,Ribonucleotide reductase 1 |
| 3 | I, N, S, X (A, B, C, D) | CYTIDINE-5'-DIPHOSPHATE | non-polymer | 403.2 | 4 | Chemie (CDP) | |||
| 4 | J, O, T, Y (A, B, C, D) | 2'-DEOXYADENOSINE-5'-DIPHOSPHATE | non-polymer | 411.2 | 4 | Chemie (DAT) | |||
| 5 | BA, K, M, P, R... (D, A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 6 | AA, L, Q, V (D, A, B, C) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 4 | Chemie (DTP) | |||
| 7 | CA, DA, EA, FA (E, F, G, H) | MU-OXO-DIIRON | non-polymer | 127.7 | 4 | Chemie (FEO) | |||
| 8 | GA, HA, IA, JA, KA... (A, B, C, D, E...) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 517215.8 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 5927.4 | |
| All* | Total formula weight | 523143.2 |
