5CLT
Crystal structure of human glycogen branching enzyme (GBE1) in complex with acarbose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | 1,4-alpha-glucan-branching enzyme | polymer | 668 | 77036.7 | 3 | UniProt (Q04446) Pfam (PF02922) Pfam (PF00128) Pfam (PF02806) | Homo sapiens (Human) | Brancher enzyme,Glycogen-branching enzyme |
| 2 | D, E, F (D, E, F) | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 645.6 | 3 | In PDB BIRD (PRD_900007) GlyTouCan (G66431MI) | alpha-acarbose |
Sequence modifications
A, B, C: 38 - 700 (UniProt: Q04446)
| PDB | External Database | Details |
|---|---|---|
| Tyr 33 | - | expression tag |
| Phe 34 | - | expression tag |
| Gln 35 | - | expression tag |
| Ser 36 | - | expression tag |
| Met 37 | - | expression tag |
| Ser 265 | Thr 265 | conflict |
| Val 334 | Ile 334 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 231110.2 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1936.8 | |
| All* | Total formula weight | 233047.0 |
