5CLS
Structure of human methionine aminopeptidase-2 complexed with spiroepoxytriazole inhibitor (+)-31a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methionine aminopeptidase 2 | polymer | 371 | 41510.1 | 1 | UniProt (P50579) Pfam (PF00557) | Homo sapiens (Human) | MetAP 2,Initiation factor 2-associated 67 kDa glycoprotein,p67eIF2,Peptidase M |
| 2 | B (A) | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 3 | C, D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 4 | E, F (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | G (A) | (4R,7R)-7-hydroxy-1-(4-methoxybenzyl)-7-methyl-4,5,6,7-tetrahydro-1H-benzotriazol-4-yl propan-2-ylcarbamate | non-polymer | 374.4 | 1 | Chemie (52T) | |||
| 6 | H (A) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 7 | I (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | J (A) | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41510.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1001.4 | |
| All* | Total formula weight | 42511.5 |
