5CL6
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (33% substrate/67% product at 72 hours)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | AlkD | polymer | 241 | 28578.0 | 1 | UniProt (R8GWR7) Pfam (PF08713) UniProt (by SIFTS) (Q816E8) | Bacillus cereus | |
| 2 | B (B) | DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3') | polymer | 12 | 3645.4 | 1 | synthetic construct | ||
| 3 | C (C) | DNA (5'-D(*CP*GP*GP*AP*CP*TP*TP*TP*CP*GP*GP*G)-3') | polymer | 12 | 3694.4 | 1 | synthetic construct | ||
| 4 | D (B) | 7-methyl-3H-imidazo[4,5-c]pyridin-4-amine | non-polymer | 148.2 | 1 | Chemie (54K) | |||
| 5 | E, F, G (A, B, C) | water | water | 18.0 | 413 | Chemie (HOH) |
Sequence modifications
A: 1 - 237 (UniProt: R8GWR7)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Val -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35917.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 148.2 | |
| All* | Total formula weight | 36066.0 |
