5CJN
Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 3-(3-oxo-3,4-dihydroquinoxalin-2-yl)acrylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Malate synthase G | polymer | 741 | 80472.7 | 1 | UniProt (P9WK17) Pfam (PF20656) Pfam (PF20658) Pfam (PF01274) Pfam (PF20659) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 2 | B, C, D, E, F... (A) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 3 | J (A) | 3-(3-oxo-3,4-dihydroquinoxalin-2-yl)propanoic acid | non-polymer | 218.2 | 1 | Chemie (52F) | |||
| 4 | K (A) | water | water | 18.0 | 548 | Chemie (HOH) |
Sequence modifications
A: 1 - 741 (UniProt: P9WK17)
| PDB | External Database | Details |
|---|---|---|
| Ala 619 | Cys 619 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 80472.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 412.6 | |
| All* | Total formula weight | 80885.4 |
