5CDW
Crystal Structure Analysis of a mutant Grb2 SH2 domain (W121G) with a pYVNV peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, E, B, C, G...) | Growth factor receptor-bound protein 2 | polymer | 100 | 11575.1 | 16 | UniProt (P62993) Pfam (PF00017) | Homo sapiens (Human) | Adapter protein GRB2,Protein Ash,SH2/SH3 adapter GRB2 |
| 2 | AA, BA, CA, DA, EA... (D, M, s, a, F...) | SER-PTR-VAL-ASN-VAL-GLN | polymer | 6 | 788.7 | 16 | Homo sapiens | ||
| 3 | GA, HA, IA, JA, KA... (A, E, B, C, G...) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A, E, B, C, G, H, K, L, O, P, U, V, Y, Z, c, d: 2 - 101 (UniProt: P62993)
| PDB | External Database | Details |
|---|---|---|
| Gly 69 | Trp 121 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 32 |
| Total formula weight | 197821.6 | |
| All* | Total formula weight | 197821.6 |
