5CCS
Human Cyclophilin D Complexed with Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | polymer | 165 | 17782.3 | 1 | UniProt (P30405) Pfam (PF00160) | Homo sapiens (Human) | PPIase F,Cyclophilin D,CypD,Cyclophilin F,Mitochondrial cyclophilin,CyP-M,Rotamase F, Human Cyclophilin D |
| 2 | B (X) | 1-(4-aminobenzyl)-3-{2-oxo-2-[(2R)-2-phenylpyrrolidin-1-yl]ethyl}urea | non-polymer | 352.4 | 1 | Chemie (C4Y) | |||
| 3 | C (X) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
X: 2 - 165 (UniProt: P30405)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gln 125 | Lys 167 | engineered mutation |
| Ile 133 | Lys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17782.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 352.4 | |
| All* | Total formula weight | 18134.7 |
