5CCN
Human Cyclophilin D Complexed with Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | polymer | 164 | 17652.1 | 1 | UniProt (P30405) Pfam (PF00160) In PDB | Homo sapiens (Human) | PPIase F,Cyclophilin D,CypD,Cyclophilin F,Mitochondrial cyclophilin,CyP-M,Rotamase F |
| 2 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 3 | A | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 4 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 6 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | A | ethyl N-{[3-(3-aminopyridin-4-yl)benzyl]carbamoyl}glycinate | non-polymer | 328.4 | 1 | Chemie (4ZZ) | |||
| 8 | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A: 2 - 165 (UniProt: P30405)
| PDB | External Database | Details |
|---|---|---|
| Ile 133 | Lys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17652.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 864.0 | |
| All* | Total formula weight | 18516.1 |
