5CCM
Crystal structure of SMYD3 with SAM and EPZ030456
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Histone-lysine N-methyltransferase SMYD3 | polymer | 428 | 49150.1 | 1 | UniProt (Q9H7B4) Pfam (PF00856) Pfam (PF01753) In PDB | Homo sapiens (Human) | SET and MYND domain-containing protein 3,Zinc finger MYND domain-containing protein 1 |
2 | A | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
3 | A | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
4 | A | 6-chloranyl-2-oxidanylidene-N-[(1S,5R)-8-[4-[(phenylmethyl)amino]piperidin-1-yl]sulfonyl-8-azabicyclo[3.2.1]octan-3-yl]-1,3-dihydroindole-5-carboxamide | non-polymer | 572.1 | 1 | Chemie (4ZX) | |||
5 | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A: 1 - 428 (UniProt: Q9H7B4)
PDB | External Database | Details |
---|---|---|
Asn 13 | Lys 13 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 49150.1 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1166.8 | |
All* | Total formula weight | 50316.9 |