5CCJ
Crystal structure of the quintuple mutant of the synaptotagmin-1 C2B domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Synaptotagmin-1 | polymer | 152 | 17017.8 | 4 | UniProt (P21707) Pfam (PF00168) In PDB | Rattus norvegicus (Rat) | Synaptotagmin I,SytI,p65 |
| 2 | A, C, D, B | GLYCEROL | non-polymer | 92.1 | 27 | Chemie (GOL) | |||
| 3 | B, D, A, C | SULFATE ION | non-polymer | 96.1 | 22 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 768 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 271 - 421 (UniProt: P21707)
| PDB | External Database | Details |
|---|---|---|
| Ser 270 | - | expression tag |
| Ala 281 | Arg 281 | engineered mutation |
| Ala 295 | Glu 295 | engineered mutation |
| Trp 338 | Tyr 338 | engineered mutation |
| Ala 398 | Arg 398 | engineered mutation |
| Ala 399 | Arg 399 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 68071.2 | |
| Non-Polymers* | Number of molecules | 49 |
| Total formula weight | 4599.9 | |
| All* | Total formula weight | 72671.1 |
